abstract：Purpose:We compared clinical characteristics of COPD patients according to symptom variability and evaluated the effect of symptom variability during the first year of enrollment on clinical outcomes of COPD. Methods:We analyzed COPD patients' data from the Korean Obstructive Lung Disease (KOLD) cohort. Symptom variab...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim MA,Suh MK,Park J,Kim JH,Kim TH,Kim EK,Oh YM,Lee SD,Lee JH

更新日期：2019-09-20 00:00:00

abstract：Background:Upper limb muscle strength plays an important role in respiratory and pulmonary function, and limited research focuses on the role of strength and endurance of the elbow extensor and flexor. This study was conducted to accurately assess upper limb muscle function and quantified associations with pulmonary fu...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu X,Li P,Wang Z,Lu Y,Li N,Xiao L,Duan H,Wang Z,Li J,Shan C,Wu W

更新日期：2019-09-05 00:00:00

abstract：Background:Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated. Methods:We studied 21 non-treated AATD (AATD-noT) patients, 20 AATD-...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balbi B,Sangiorgi C,Gnemmi I,Ferrarotti I,Vallese D,Paracchini E,Delle Donne L,Corda L,Baderna P,Corsico A,Carone M,Brun P,Cappello F,Ricciardolo FL,Ruggeri P,Mumby S,Adcock IM,Caramori G,Di Stefano A

更新日期：2019-08-21 00:00:00

abstract：Purpose:Waterpipe (WP) use has become a global trend in young populations. However, there are few well-controlled studies focusing specifically on the chronic effects of exclusive WP use on young adults' respiratory health. We sought to compare in young adults the burden of respiratory symptoms in regular WP smokers (W...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hawari FI,Obeidat NA,Abu Alhalawa M,Al-Busaidi Z,Amara B,Baddar S,Elhabiby M,Elkholy H

更新日期：2019-08-13 00:00:00

abstract：:Backgroud and objectives: Although lung attenuation distribution and lung volume on computed tomography (CT) have been widely used in evaluating COPD and interstitial lung disease, there are only a few studies regarding the normal range of these indices, especially in Chinese subjects. We aimed to describe the normal ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cheng T,Li Y,Pang S,Wan H,Shi G,Cheng Q,Li Q,Pan Z,Huang S

更新日期：2019-07-24 00:00:00

abstract：Purpose:Acute exacerbation of COPD (AECOPD) is among the most frequent causes for hospital admission, causing morbidity and mortality. Infection is the most frequent cause, and studies on pollution have shown higher hospital admission and mortality with inconsistent results. The objective was to identify if there is a ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Morantes-Caballero JA,Fajardo Rodriguez HA

更新日期：2019-07-11 00:00:00

abstract：Objective:Chronic obstructive pulmonary disease (COPD) is associated with atherosclerosis. Previous studies including limited sample sizes have shown the prevalence of peripheral arterial occlusive disease (PAOD) among COPD patients. We sought to investigate the incidence of PAOD among COPD patients in Taiwan using a n...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liao KM,Kuo LT,Lu HY

更新日期：2019-07-04 00:00:00

abstract：:Background: Qualitative research provides real-life information on patients' condition and facilitates informed design of future clinical studies. Objective: We used Online Communities as a qualitative research tool to evaluate the effect of cough and mucus on COPD patients. Methods: Two 2-week Online Communities were...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cook N,Gey J,Oezel B,Mackay AJ,Kumari C,Kaur VP,Larkin N,Harte J,Vergara-Muro S,Gutzwiller FS

更新日期：2019-06-24 00:00:00

abstract：:Background: Pulmonary hypertension (PH) is one of the most common complications developed during the course of chronic obstructive pulmonary disease (COPD). Platelet activation plays an important role in its pathophysiology, and mean platelet volume (MPV) is considered a respectable index of platelet activation. The a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mohamed MF,Ali A,Abbas A,Awad MS,Gouda M,Sediq AM

更新日期：2019-05-23 00:00:00

abstract：:Objectives: COPD is the fourth-leading cause of mortality worldwide. Prolonged QTc has been found to be a long-term negative prognostic factor in ambulatory COPD patients. The aim of this study was to evaluate the extent of prolonged-QTc syndrome in COPD patients upon admission to an internal medicine department, its ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zilberman-Itskovich S,Rahamim E,Tsiporin-Havatinsky F,Ziv-Baran T,Golik A,Zaidenstein R

更新日期：2019-05-20 00:00:00

abstract：:Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released an updated document in 2017 that excluded the spirometric parameter in the classification of patients. The validity of this new classification system in predicting mortality and respiratory hospitalization is still uncertain. Method...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee SJ,Yun SS,Ju S,You JW,Cho YJ,Jeong YY,Kim JY,Kim HC,Lee JD

更新日期：2019-04-29 00:00:00

abstract：:Background: There are currently limited real-world data on the clinical burden of illness in patients with COPD who continue to exacerbate despite receiving triple therapy. The aim of this study was to compare the burden of COPD in patients with and without a phenotype characterized by a high blood eosinophil count an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Müllerová H,Meeraus WH,Galkin DV,Albers FC,Landis SH

更新日期：2019-03-28 00:00:00

abstract：Purpose:Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. Decreased baroreflex sensitivity (BRS) and increased blood pressure (BP) variability (BPV) are markers of impaired cardiovascular autonomic regulation and there is evidence for an association between decreased BRS/i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwarz EI,Latshang TD,Furian M,Flück D,Segitz S,Müller-Mottet S,Ulrich S,Bloch KE,Kohler M

更新日期：2019-03-14 00:00:00

abstract：Objective:Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods:A total of 543 patients with COPD (FEV1 <80% and FEV1/FVC <70%) were included between January 2003 and January 2004. Patients were stable for at least 6 weeks before inclusion and were followed for 5 yea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Aramburu A,Arostegui I,Moraza J,Barrio I,Aburto M,García-Loizaga A,Uranga A,Zabala T,Quintana JM,Esteban C

更新日期：2019-03-07 00:00:00

abstract：Introduction and aim:Abnormal brain structure and function in COPD has been reported on MRI. However, the deficit in local synchronization of spontaneous activity in patients with stable COPD remains unknown. The main aim of the present study was to explore spontaneous brain activity in patients with COPD compared with...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xin H,Li H,Yu H,Yu J,Zhang J,Wang W,Peng D

更新日期：2019-02-27 00:00:00

abstract：Background:COPD may lead to cognitive impairment or even dementia. However, the current conclusions are inconsistent with little evidence from prospective, large-sample studies. This study was designed to explore the association of COPD with mild cognitive impairment (MCI) and dementia risk based on a cohort study. Pa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xie F,Xie L

更新日期：2019-02-13 00:00:00

abstract：:[This corrects the article on p. 1401 in vol. 12, PMID: 28546748.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2019-01-18 00:00:00

abstract：Purpose:This study investigated the effect of dual bronchodilation with the long-acting β-receptor agonist/long-acting muscarinic antagonist combination, indacaterol/glycopyrronium (IND/GLY), on nighttime oxygenation, lung function, sleep quality, and symptoms in patients with moderate-to-severe COPD. Patients and met...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lehmann S,Ringbæk T,Løkke A,Grote L,Hedner J,Lindberg E

更新日期：2019-01-09 00:00:00

abstract：Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

更新日期：2018-12-28 00:00:00

abstract：Purpose:The aim of this study was to examine real-world differences in health care resource use (HRU) and costs among COPD patients in the USA treated with a dry powder inhaler (DPI) or pressurized metered-dose inhaler (pMDI) following a COPD-related hospitalization. Methods:This retrospective analysis used the Truven...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wittbrodt ET,Millette LA,Evans KA,Bonafede M,Tkacz J,Ferguson GT

更新日期：2018-12-24 00:00:00

abstract：Background:Frailty can inform management approaches for individuals with COPD. However, inpatient measures of frailty are seldom employed because they are time-consuming or inapplicable for bed-bound patients. We investigated the feasibility and potential of an innovative sensor-based upper-extremity function (UEF) tes...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ehsani H,Mohler MJ,Golden T,Toosizadeh N

更新日期：2018-12-18 00:00:00

abstract：:[This corrects the article on p. 3485 in vol. 13, PMID: 30498338.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-12-05 00:00:00

abstract：Background:In COPD disturbed sleep is related to exacerbation frequency, poor quality of life, and early mortality. We developed the Manchester Respiratory-related Sleep Symptoms scale (MaRSS) to assess sleep-time symptoms in COPD. Methods:Focus groups including COPD and age-matched controls were used to develop an it...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Khan N,Vestbo J,Garrow A,Karur P,Kolsum U,Tyson S,Singh D,Yorke J

更新日期：2018-11-29 00:00:00

abstract：Purpose:miR-190a-5p expression alters dynamically in response to hypoxia. However, the role of miR-190a-5p expression in hypoxia-induced pulmonary hypertension (PH) remains unclear. We sought to correlate the miR-190a-5p expression levels with the severity, diagnosis, and prognosis of PH in relation to chronic obstruct...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jiang J,Xia Y,Liang Y,Yang M,Zeng W,Zeng X

更新日期：2018-11-20 00:00:00

abstract：Background:Microparticles (MPs) are shedding membrane vesicles released from activated blood and endothelial cells under inflammatory conditions. The role of endothelial MPs (EMPs) in pathophysiology of COPD is relatively well known. However, the release and function of MPs of other cellular origins, eg, platelets, red...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tőkés-Füzesi M,Ruzsics I,Rideg O,Kustán P,Kovács GL,Molnár T

更新日期：2018-11-15 00:00:00

abstract：Background:This study examines the effects of the COPD-specific health promoting self-management intervention "Better living with COPD" on different self-management-related domains, self-efficacy, and sense of coherence (SOC). Methods:In a randomized controlled design, 182 people with COPD were allocated to either an ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bringsvor HB,Langeland E,Oftedal BF,Skaug K,Assmus J,Bentsen SB

更新日期：2018-11-08 00:00:00

abstract：:[This corrects the article on p. 2147 in vol. 13, PMID: 30034230.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-10-30 00:00:00

abstract：Background:The use of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD) decreases the frequency of COPD exacerbations. Recently, pneumonia was reported as a complication of ICS in patients with COPD. However, there have been few reports concerning the relationship between ICS an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hirano R,Fujita M,Matsumoto T,On R,Watanabe K

更新日期：2018-10-23 00:00:00

abstract：Purpose:Improvement in the diagnosis of asthma and chronic obstructive pulmonary disease (COPD) overlap (ACO), and identification of biomarkers for phenotype recognition will encourage good patient care by providing optimal therapy. We investigated club cell secretory protein (CC-16), a protective and anti-inflammatory...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Oh JY,Lee YS,Min KH,Hur GY,Lee SY,Kang KH,Rhee CK,Park SJ,Shim JJ

更新日期：2018-10-18 00:00:00

abstract：Purpose:Whole-body vibrating training (WBVT) is a modality aiming to improve neuromuscular performance of patients with COPD. However, a consensus on the effects of WBVT has not been reached. We aimed to clarify the effects of WBVT on functional exercise capacity, pulmonary function, and quality of life in COPD patient...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou J,Pang L,Chen N,Wang Z,Wang C,Hai Y,Lyu M,Lai H,Lin F

更新日期：2018-10-10 00:00:00

abstract：Background:Exacerbations explain much of the cost of COPD. Higher blood eosinophil cell counts at admission for acute exacerbation of COPD increase the risk of subsequent exacerbations and hospitalizations. However, there is no literature on the economic burden of patients with this inflammatory profile. The objective ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Poder TG,Carrier N,Bélanger M,Couillard S,Courteau J,Larivée P,Vanasse A

更新日期：2018-10-08 00:00:00

abstract：Purpose:The primary aim of this research was to raise awareness for COPD through real narratives of patients, caregivers, and pulmonologists. The second objective includes providing clinicians new means of caring for and treating patients with COPD. Methods:Using narrative medicine, testimonies from patients, their ca...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gatti V,Banfi P,Centanni S,D'Antonio S,Giustini S,Piraino A,Zibellini M,Marini MG

更新日期：2018-10-05 00:00:00

abstract：Background:Previous studies suggest that gender differences exist in COPD diagnosis and symptoms; these differences may be more pronounced in younger adults. Our objective was to explore age-associated gender differences across a range of COPD severities. Materials and methods:A total of 4,484 current and former smoke...

journal_title：International journal of chronic obstructive pulmonary disease

authors： DeMeo DL,Ramagopalan S,Kavati A,Vegesna A,Han MK,Yadao A,Wilcox TK,Make BJ,COPDGene Investigators.

更新日期：2018-10-01 00:00:00

abstract：Background:Phase III studies demonstrated efficacy and safety of nebulized glycopyrrolate inhalation solution (GLY) in subjects with COPD. Secondary analyses were performed to examine the effect of background long-acting beta2-agonist (LABA) use on the efficacy and safety of nebulized GLY. Methods:In two 12-week place...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kerwin EM,Tosiello R,Price B,Sanjar S,Goodin T

更新日期：2018-09-19 00:00:00

abstract：Purpose:Psychiatric patients present an elevated rate of smoking, and the smoking habit is related to a high morbidity and mortality in this collective. The aim of this study was to determine the prevalence of smoking in patients admitted for psychiatric disorders and its relationship with respiratory disease, the prev...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lores L,Monje A,Bergada M,Arellano E,Rodríguez-Larrea J,Miravitlles M

更新日期：2018-09-07 00:00:00

abstract：Introduction:Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily durati...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sundh J,Ahmadi Z,Ekström M

更新日期：2018-08-28 00:00:00

abstract：Background:Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. Aim:We present findings from a long-term prospective assessment of respiratory parameters in a cohort of COPD patients who ceased or substantially reduced conventional cigare...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Polosa R,Morjaria JB,Prosperini U,Russo C,Pennisi A,Puleo R,Caruso M,Caponnetto P

更新日期：2018-08-22 00:00:00

abstract：Purpose:COPD has been associated with a high number of comorbidities and a relatively high level of health care resource utilization. This study aimed to estimate the social economic impact of COPD in the autonomous community of Extremadura (Spain) in 2015. Patients and methods:This is a retrospective observational st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Merino M,Villoro R,Hidalgo-Vega Á,Carmona C

更新日期：2018-08-21 00:00:00

abstract：Background:Telerehabilitation (TR) aimed at patients with COPD has shown promising effects on symptoms, physical function, and quality of life, but little research has been conducted to understand the impact of implementation on frontline health professionals. Therefore, the aim of this study was to examine the barrier...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Damhus CS,Emme C,Hansen H

更新日期：2018-08-17 00:00:00

abstract：Purpose:The unpredictable trajectory of COPD can present challenges for patients when faced with a decision regarding a do-not-resuscitate (DNR) directive. The current retrospective analysis was conducted to investigate factors associated with an early DNR decision (prior to last hospital admission) and differences in ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fu PK,Tung YC,Wang CY,Hwang SF,Lin SP,Hsu CY,Chen DR

更新日期：2018-08-14 00:00:00